Staphylococci: types, infections, and treatment

The date

Jun 05, 2024

Staphylococci

Staphylococci are round bacteria, approximately 1 micrometer in size, characterized by their grape-like clusters (the name originates from the Greek god of wine, Dionysus). The Staphylococcus genus includes numerous species, most of which are non-pathogenic. These bacteria are widespread in nature and commonly found on human skin and mucous membranes.

The most common types of staphylococci

Three types of staphylococci are the most common and medically significant:

  • Staphylococcus aureus (golden staphylococcus)
  • Staphylococcus epidermidis
  • Staphylococcus saprophyticus

Staphylococcus aureus (golden staphylococcus)

Staphylococcus aureus is the most well-known and frequently isolated bacterium in microbiology laboratories. It can cause a wide range of infections, including:

  • Skin infections (abscesses, exfoliative dermatitis in newborns)
  • Wound infections, middle ear infections, and eye infections (blepharitis, conjunctivitis)
  • Pneumonia (staphylococcal pneumonia)
  • Infections of other tissues and organs
  • Staphylococcal tonsillitis
  • Peritonsillar abscess

Staphylococcus aureus can also lead to severe complications such as food poisoning and toxic shock syndrome (TSS), which is most commonly linked to genital infections.

Due to increasing antibiotic resistance, strains resistant to treatment are becoming more common. One of the most significant strains is methicillin-resistant Staphylococcus aureus (MRSA), which is resistant to most penicillins and cephalosporins.

Staphylococcus epidermidis

Staphylococcus epidermidis is usually non-pathogenic, but in some cases, it can cause endocarditis. Severe endocardial infections may occur, particularly after the placement of artificial heart valves.

Staphylococcus saprophyticus

Staphylococcus saprophyticus is a common inhabitant of the skin and the mucous membranes of the urinary tract. Although it usually does not cause problems, it can lead to urinary tract infections (UTIs), particularly in sexually active women. This bacterium is increasingly recognized as a significant cause of UTIs, second only to Escherichia coli.

Diagnosis is based on colony morphology, the absence of hemolysis, and resistance to novobiocin. Treatment is guided by antibiotic susceptibility testing, and the infection generally responds well to antibiotics and urinary antiseptics, such as:

  • Cephalexin
  • Gentamicin
  • Ciprofloxacin
  • Trimethoprim + sulfamethoxazole
  • Nitrofurantoin
  • Amoxicillin + clavulanic acid

The likelihood of reinfection is low.